Registration Dossier

Diss Factsheets

Physical & Chemical properties

Dissociation constant

Currently viewing:

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Dissociation Constants of Organic Acids and Bases
Author:
Lide DR
Bibliographic source:
Lide DR (ed.) CRC Handbook of Chemistry and Physics (82nd), 2001-2002, Boca Raton, London, New York, Washington D.C., p 8-51

Materials and methods

Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
p-toluidine
EC Number:
203-403-1
EC Name:
p-toluidine
Cas Number:
106-49-0
Molecular formula:
C7H9N
IUPAC Name:
p-toluidine
Details on test material:
- Name of test material (as cited in study report): 4.Methylaniline
- Analytical purity: not specified

Results and discussion

Dissociation constant
pKa:
5.08
Temp.:
25 °C
Remarks on result:
other: expressed as acidity of the conjugate acid

Any other information on results incl. tables

no further data

Applicant's summary and conclusion