Registration Dossier
Registration Dossier
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EC number: 203-603-9 | CAS number: 108-65-6
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Propylene glycol methyl ether acetate meets the criteria for ready biodegradation, based on the results of several aerobic biodegradation screening tests (e.g. 83% degradation in the manometric respirometry test). In conclusion, propylene glycol methyl ether acetate can be considered as readily biodegradable under aerobic conditions. Hence, the test substance does not fulfill the criteria for persistency as outlined in Annex XIII of the REACH legislation of December 2006.
Propylene glycol methyl ether acetate has a low log Kow (log Kow = 1.2) and is readily biodegradable, which indicates that propylene glycol methyl ether acetate offers little potential for bioconcentration in aquatic organisms. Therefore it does not fulfill the criteria for bioaccumulation as outlined in Annex XIII of REACH legislation of December 2006.
Measured aquatic toxicity data indicate that propylene glycol methyl ether acetate presents a low toxicity hazard to aquatic species. All EC50/LC50 values (fish, daphnia and algae) are greater than 100 mg/l.
Propylene glycol methyl ether acetate is not classified as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2) and there is no evidence of chronic toxicity, as identified by the classifications STOT (repeated exposure), category 1(oral, dermal, inhalation of gases/vapours, inhalation of dust/mist/fume) or category 2 (oral, dermal, inhalation of gases/vapours, inhalation of dust/mist/fume) according to Regulation (EC) No 1272/2008.
Therefore, this substance is not PBT.
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