Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-426-2 | CAS number: 140-66-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: terrestrial
Administrative data
Link to relevant study record(s)
Description of key information
The bioconcentration factor (BCF) for earthworms is calculated using measured LogKow data as there are no experimental earthworm data available. The measured LogKow is provided in Section 4 as 4.8 (Spilker, 2009). The calculated BCF is 758. This results in a default biomagnification factor (BMF) of 1.
Key value for chemical safety assessment
- BCF (terrestrial species):
- 758 dimensionless
Additional information
Determination of a bioconcentration factor (BCF) follows Guidance on Information Requirements and Chemical Safety Assessment Chapter R.16: Environmental Exposure Estimation (ECHA 2008) and Chapter R. 7c Endpoint Specific Guidance (ECHA 2008). Chapter R.16.5.3.5 states that there may be bioaccumulation potential if log Kow is >3. The log Kowof octylphenol is provided by Spilker (2009) as 4.8. Therefore, as per REACH Annex IX, bioaccumulation information must be presented for substances manufactured or imported in quantities of 100 t/y or more.
Chapter R.7c states that BCFs can be determined experimentally, by calculation using Kow, or by estimating using BCF models such as QSARs. There is no experimental data available for terrestrial organisms so the BCF is calculated using the Kow. The BCF is calculated using the ECHA Equation R.16-76, which is BCF earthworm = (0.84+0.012Kow)/RHO earthworm. The RHOearthworm by default value of 1 (kg wwt/L) can be assumed.
Calculated BCF
BCF earthworm = (0.84+0.012Kow)/RHO earthworm
BCF calculation using logKow of 4.8 (Kow is 63095.73)
BCF earthworm = 0.84+(0.012*63095.73)/1
BCF earthworm = 757.99
The BCF of 758 for earthworms indicates that octylphenol has a low tendency to accumulate in terrestrial organisms. This value is recommended for octylphenol bioconcentration in this risk assessment and does not meet the B-criterion in the PBT assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.