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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

L(E)C50 value for immobility was 0.13 mg octylphenol/L for Gammarus pulex (Sims and Whitehouse 1998)
 Cripe et al.(1989) reported 96 hr LC50 of 0.47 mg/L

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.013 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
0.048 mg/L

Additional information


Reliable toxicity data for aquatic invertebrate exposure to octylphenol from 48 to 96 hours included three studies with data for two freshwater and one marine species with immobility or survival test endpoints expressed as L(E)C50concentration. The range of L(E)C50values for immobility was 0.13 mg octylphenol/L for Gammarus pulex (Sims and Whitehouse 1998) to 0.28 mg/L for Ceriodaphniadubia (Isidori et al., 2006). Sims and Whitehouse (1998) distinguished between immobility (EC50) and survival (LC50) and reported a survival endpoint LC50of 0.0196 mg/L for Ceriodaphia dubia.  Cripe et al.(1989) reported LC50range of 0.048 – 0.113 mg/L for survival of the marine species Mysidopsis bahia at 96 hr exposure to octylphenol. 


The Sims and Whitehouse (1998) study was selected as the key study because the study was well documented and provided endpoints that distinguished between immobility and survival. Endpoint L(E)C50concentrations reported by the supporting studies of Isidori et al., (2006) and Cripe et al.(1989) were similar to findings of the key study.