Acetonitrile

Biodegradation in water and sediment: simulation tests

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

biodegradation in water: sewage treatment simulation testing

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Remarks:

Limited information available. Not a widely recognized data source

Principles of method if other than guideline:

No information available.

GLP compliance:

no

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, adapted

Initial conc.:

139 mg/L

Based on:

test mat.

Details on study design:

- Test temperature: 22 to 25 deg C

% Degr.:

> 98

Parameter:

other: oxygen demand

Sampling time:

28 d

% Degr.:

> 70

Parameter:

other: theoritical oxidation

Sampling time:

28 d

Following 28 days acclimation acetonitrile was introduced to activated sludge as a continuous feed with effluent removal. The study was conducted at 22-25 degree C. Degradation (>98% removal) was based on the difference between the influent and effluent oxygen demands, while theortetical oxidation (>70%) was based on the ratio of observed oxygen demand and theoretical oxygen demand.

Executive summary:

Following 28 -day acclimation, Ludzack (1960) reported >98% removal of acetonitrile introduced to activated sludge as a continuous feed with effluent removal. The study was conducted at 22-25 degrees C. Removal of acetonitrile was based on the difference between the influent and effluent oxygen demands. Theoretical oxidation (>70%) was based on the ratio of observed oxygen demand and theoretical oxygen demand.

Reference 2

Endpoint:

biodegradation in water: sediment simulation testing

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is readily biodegradable

Reference 3

Endpoint:

biodegradation in water: simulation testing on ultimate degradation in surface water

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is readily biodegradable

Description of key information

Early tests reported >98% removal of acetonitrile introduced to activated sludge as a continuous feed with effluent removal.  A waiver from further simulation testing in water and sediment is requested.

Additional information

Following 28 -day acclimation, Ludzack (1960) reported >98% removal of acetonitrile introduced to activated sludge as a continuous feed with effluent removal. The study was conducted at 22-25 °C. Removal of acetonitrile was based on the difference between the influent and effluent oxygen demands. Theoretical oxidation (>70%) was based on the ratio of observed oxygen demand and theoretical oxygen demand.

A waiver from further simulation testing in water and sediment is requested on the basis of this early study and the fact that acetonitrile is readily biodegradable in reliable screening tests.