Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Sensitisation data (human)

Currently viewing:

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
The MAK-Collection Part I: MAK Value Documentations, Vol. 24.
Author:
Deutsche Forschungsgemeinschaft
Year:
2007
Bibliographic source:
DFG, Deutsche Forschungsgemeinschaft, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Materials and methods

Type of sensitisation studied:
skin
Study type:
survey
Test guideline
Qualifier:
no guideline followed

Test material

Constituent 1
Chemical structure
Reference substance name:
Cyanoguanidine
EC Number:
207-312-8
EC Name:
Cyanoguanidine
Cas Number:
461-58-5
Molecular formula:
C2H4N4
IUPAC Name:
1-cyanoguanidine
Test material form:
solid: particulate/powder

Method

Type of population:
occupational
Route of administration:
dermal

Results and discussion

Applicant's summary and conclusion

Conclusions:
According to the MAK Collection for Occupational Health and Safety (2003) available data from occupation exposure to Dicyandiamide do not indicate a significant potential for skin sensitization.
Executive summary:

According to the MAK Collection for Occupational Health and Safety (2003) available data from occupation exposure to Dicyandiamide do not indicate a significant potential for skin sensitization.