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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2000

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
yes
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Specific details on test material used for the study:
WAKO Pure Chemicals Industries, Ltd. (Lot. PAL0299)
Purity: 99.3%

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
-0.15
Temp.:
25 °C
pH:
>= 6.2 - <= 6.3

Any other information on results incl. tables

Results:
LOG POW
-----------------------------------------------------------
Test A B Average
-----------------------------------------------------------
No.1 -0.13 -0.15
(6.3) (6.2)
No.2 -0.17 -0.17 -0.15
(6.2) (6.2)
No.3 -0.13 -0.13 (6.2) (6.2)
-----------------------------------------------------------
() is pH of water layer

Applicant's summary and conclusion

Conclusions:
The partition coefficient n-octanol/water was determined according to OECD 107 (Flask-shake method). Log Pow = - 0.15 at 25 °C.
Executive summary:

The partition coefficient n-octanol/water was determined according to OECD 107 (Flask-shake method). Log Pow = - 0.15 at 25 °C.