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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Study period:
April 1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1979

Materials and methods

Principles of method if other than guideline:
other: Range-finding-Test
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Methacrylamide
EC Number:
201-202-3
EC Name:
Methacrylamide
Cas Number:
79-39-0
Molecular formula:
C4H7NO
IUPAC Name:
methacrylamide
Test material form:
solid
Details on test material:
Batch (Lot) Number: 11110320

Test animals

Species:
mouse
Strain:
NMRI
Sex:
female

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
arachis oil
Doses:
2- or 4 % methacrylamide emulsion in oleum arachidis (peanut oil)
No. of animals per sex per dose:
2

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD100
Effect level:
1 200 mg/kg bw

Applicant's summary and conclusion