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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

LC50 = 2.02 mg/L (OECD Guideline 203, static renewal; GLP, RL1)

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
2.02 mg/L

Additional information

In a 96 h acute toxicity study according to OECD guideline 203, adopted 17 July 1992, Zebrafish (Danio rerio) were exposed to Epoxy half acrylate (100% a.i.) at nominal concentrations of 0, 0.625, 1.25, 2.50, 5.00 and 10.0 mg/L, corresponding to geometric mean weighted loading levels of 0, 0.239, 0.599, 1.25, 3.27 and 4.98 mg/L under semi-static conditions with daily renewal. 7 test organisms were exposed to each loading level and the control.

The concentrations of the analytes of the test item were analytically verified by LC-MS/MS from freshly prepared test media after 0 and 72 hours and corresponding 24 h aged test media after 24 and 96 hours of all concentration levels and the control.

Effect levels are given based on overall geometric mean weighted test item loadings.

100% mortality was observed at 4.98 mg/L. Sublethal effects (hyperventilation and missing escape reflex) were observed at a concentration of 3.27 mg/L. No mortality or sublethal effects were present at up to 1.25 mg/L.

The 96 h LC50 was 2.02 mg/L (95% CL: 1.25-3.27 mg/L).