Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 407-770-0 | CAS number: 61597-96-4 D(+)-LACTATE D'ISOBUTYLE
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
In vivo, isobutyl-R-lacate is rapidly hydrolysed enzymatically. Therefore, the toxicologically relevant compounds following systemic uptake are lactic acid/lactate (low toxicological concern) and isobutanol.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
Isobutyl-R-lactate, as all lactate esters, is rapidly hydrolysed in vivo into lactic acid and isobutanol.
Lactic acid is a ubiquitous and essential biological molecule, in humans and other mammals, but also in most if not all vertebrate and invertebrate animals, as well as in many micro-organisms. Therefore the biokinetics, metabolism and distribution of lactic acid have to be considered in the context of its normal biochemistry; lactic acid is of minor toxicological concern given its ubitquitousness and function as a common metabolite.
Isobutanol is an alcohol that is metabolised by the normal alcohol metabolism pathways.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
