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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

The predicted data from QSAR Toolbox version 3.4 suggests the Inhibition growth concentration (IGC50) for the substance Octyl acetate (CAS no.112-14-1) was estimated to be 146.613647461 mg/l on micro organism Tetrahymena pyriformis on the basis of growth inhibition effect in static fresh water.

Key value for chemical safety assessment

EC50 for microorganisms:
146.61 mg/L

Additional information

Predicted model data and Experimental study result of toxicity to micro organism for the target chemical Octyl acetate (CAS no. 112-14-1) were reviewed to summarize the following information:


From predicted model the 48 hrs aquatic toxicity study was predicted to assess toxic effects of the test compound Octyl acetate (CAS no. 112-14-1) and the result were predicted (SSS QSAR Prediction model, 2016). The study was based on the effects of the test compound on Tetrahymena pyriformis micro organism in a static fresh water system. The predicted data suggests the Inhibition growth concentration (IGC50) for the test compound was estimated to be 146.613647461 mg/l on the basis of growth inhibition effect. Since the test chemical is readily biodegradable in nature it can be considered as the test substance Octyl acetate has no concern for aquatic toxicity.     


And read across Butyl acetate (Cas no. 123-86-4) in experimental study indicate that the toxicity study for micro organism Uronema parduczi (Ciliate) was conduct for exposure period 20 hrs. the effect concentration was observed to be 574 mg/l on the basis of population effect. (ECOTOX database; 2016)


 Thus based on the above available studies it is concluded that the test substance Octyl acetate (CAS no. 112-14-1) have no concern for micro organism toxicity.