Registration Dossier
Registration Dossier
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EC number: 203-397-0 | CAS number: 106-43-4
Endpoint summary
Administrative data
Description of key information
2 valid studies are available for skin irritation. As a result p-chlorotoluene is not irritant to the skin
Also 2 valid studies are available for eye irritation. In these studies p-chlorotoluene was slightly irritating to the eyes
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
in the key studies (skin irritation) p-chlorotoluene was not irritating
in the key study (eye irritation irritation) of p-chlorotoluene
the mean value of the cornea score (24, 48, 72 h) = 0
the mean value of the iris score (24, 48, 72 h) = 0
the mean value of the conjunctiva score (24, 48, 72 h) = 0.72
the mean value of the chemosis score (24, 48, 72 h) = 0.5
Justification for classification or non-classification
Due to the result of the key studies for skin and eye irritation a classification is not justified
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