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EC number: 222-720-6 | CAS number: 3586-55-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
The bioconcentrations in aquatic organisms was estimated according to a QSAR model.
Additional information
Data on formaldehyde
Accumulation
One recent study on marine fish is available in which tissue formaldehyde levels after exposure to formaldehyde were investigated. Elevated formaldehyde levels in muscle tissue (by 0.8 µg/g wet weight) were found only directly after a one-hour treatment at 185 mg/L, but not after a 24-hour or longer depuration period. Assuming that one hour was sufficient to reach steady-state conditions a BCF of 4 x 10-6 was calculated, however, reliability of that value has to remain questionable. The study was conducted to investigate formaldehyde concentrations in fish after typical antiparasitical treatments in aquaculture, but aimed not at the determination of a BCF for formaldehyde.
Two older studies are cited in WHO (2002) and OECD (2002), in which no elevated formaldehyde contents were found after a one or three–hour treatments at 121 mg/L in marine and freshwater fish tissue, and after 24 hours of treatment (50 and 150 mg/L) in marine shrimp tissue. Shrimp tail muscle was found to produce small amounts of formaldehyde during postmortem decomposition.
Additional information on logPow as well as the estimated BCFfish and biomagnification factor for fish-eating predators support the experimental findings that formaldehyde does not bioconcentrate in aquatic biota.
There is no study available on accumulation of formaldehyde in terrestrial organisms. Therefore, the BCF for earthworms was estimated according a QSAR model described in EU Technical Guidance Document on Risk Assessment (EC 2003). As the value is very low, bioaccumulation potential is not expected for terrestrial organisms.
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