Disodium 2-oxoglutarate

Flammability

Administrative data

Endpoint:

self-heating substances / mixtures

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 - 22 March 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

other: UN Recommendations on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria

Version / remarks:

Rev. 6 (2015)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

other: VDI 2263 Sheet 1 Grewer Oven

Version / remarks:

1990

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Disodium 2-oxoglutarate

EC Number:

206-167-8

EC Name:

Disodium 2-oxoglutarate

Cas Number:

305-72-6

Molecular formula:

C5H6O5.2Na

IUPAC Name:

disodium 2-oxopentanedioate

impurity 1

Reference substance name:

Water

EC Number:

231-791-2

EC Name:

Water

Cas Number:

7732-18-5

Molecular formula:

H2O

IUPAC Name:

Oxidane

Test material form:

solid: crystalline

Remarks:

Crystalline powder

Details on test material:

Batch No: 14152300
Storage: 15 – 25 °C

Results and discussion

Self-heating substances / mixtures

Self-heating substances / mixtures 1

Key result

Test procedure:

other: Grewer oven

Remarks:

pure test item

Max. temp. reached:

230

Result:

other: no significant temperature increase was observed starting at 200°C

Remarks on result:

other: on the basis of the results, the test item cannot be classified. Further tests are needed.

Self-heating substances / mixtures 2

Key result

Test procedure:

other: Grewer oven

Remarks:

test item in mixture with Kieselgur

Max. temp. reached:

220

Result:

other: no significant temperature increase was observed starting at 200°C

Remarks on result:

other: on the basis of the results, the test item cannot be classified. Further tests are needed.

Any other information on results incl. tables

In the investigation of self-ignition in the Grewer Oven for the pure test item a small exothermic process was detected starting at 200 °C. This self-heating did not lead to a significant temperature increase (30 °C above the corresponding temperature of the reference material). A black residue remained in the wire basket after the test.

For the test item in mixture with Kieselguhr also a small exothermic effect was observed starting at 200 °C, which also did not lead to a significant temperature increase (20 °C above the corresponding temperature of the reference material).

Applicant's summary and conclusion

Interpretation of results:

study cannot be used for classification

Conclusions:

The pure test item Alpha-Ketoglutarate disodium salt (CAS no. 305-72-6) indicated a self-heating at atmospheric pressure starting at a temperature of 200 °C. This self-heating process did not lead to a significant temperature increase.
On the basis of the results of the tests on the self-ignition in the Grewer Oven according to the UN Recommendations on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria, Appendix 6 Division 4.2, a classification of the test item as self-heating substance cannot be excluded. Further tests have to be performed for the classification.

Executive summary:

The pure test item Alpha-Ketoglutarate disodium salt (CAS no. 305 -72 -6) indicated a self-heating at atmospheric pressure starting at a temperature of 200 °C. This self-heating process did not lead to a significant temperature increase.

On the basis of the results of the tests on the self-ignition in the Grewer Oven according to the UN Recommendations on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria, Appendix 6 Division 4.2, a classification of the test item as self-heating substance cannot be excluded. Further tests have to be performed for the classification.