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EC number: 206-167-8 | CAS number: 305-72-6
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 March 2017 - 22 May 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: 2 effusion methods: Vapour pressure balance and Knudsen cell
Test material
- Reference substance name:
- Disodium 2-oxoglutarate
- EC Number:
- 206-167-8
- EC Name:
- Disodium 2-oxoglutarate
- Cas Number:
- 305-72-6
- Molecular formula:
- C5H6O5.2Na
- IUPAC Name:
- disodium 2-oxopentanedioate
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- Oxidane
- Test material form:
- solid: crystalline
- Remarks:
- Crystalline powder
- Details on test material:
- Batch No: 14152300
Storage: 15 – 25 °C
Constituent 1
impurity 1
Results and discussion
Vapour pressureopen allclose all
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- < 0.02 Pa
- Remarks on result:
- other: calculated by extrapolation
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- < 0.02 Pa
- Remarks on result:
- other: calculated by extrapolation
- Key result
- Temp.:
- 50 °C
- Vapour pressure:
- < 0.02 Pa
- Remarks on result:
- other: calculated by extrapolation
Any other information on results incl. tables
Effusion method: Knudsen-Cell
The vapour pressure was determined for 13 temperatures in the temperature range of 20 – 130 °C. Due to the fact that the test item showed no proper linear correlation of the vapour pressure and the inverse temperature 1/T, the Antoine constants cannot be evaluated in the measured temperature range. Since no evaluable vapour pressure curve could be determined a further test series was performed using the vapour pressure balance.
Vapour pressure balance:
With the vapour pressure balance method, the vapour pressure was determined for 14 temperatures in the temperature range of 37 – 163 °C. Due to the fact that the test item showed no proper linear correlation of the vapour pressure and the inverse temperature 1/T, the Antoine constants cannot be evaluated in the measured temperature range.
Due to the results of both effusion methods, the vapour pressures for the temperatures 20, 25 and 50 °C are estimated on the basis of the maximum measured vapourpressures of 2.01 × 10-2 Pa at temperatures of 153 °C.
Applicant's summary and conclusion
- Conclusions:
- The test item Alpha-Ketoglutarate disodium salt (CAS no. 305-72-6) showed no evaluable vapour pressure curve in the temperature range of 20 to 163 °C. Due to this result, the vapour pressures for the temperatures 20, 25 and 50 °C are estimated on the basis of the maximum vapour pressures measured by the vapour pressure balance, according to Regulation EC No. 440/2008 Method A.4. Vapour Pressure and OECD Test Guideline 104 (2006).
The vapour pressure of the test item was < 0.02 Pa at 20°C, 25°C and at 50°C. - Executive summary:
The test item Alpha-Ketoglutarate disodium salt (CAS no. 305-72-6) showed no evaluable vapour pressure curve in the temperature range of 20 to 163 °C. Due to this result, the vapour pressures for the temperatures 20, 25 and 50 °C are estimated on the basis of the maximum vapour pressures measured by the vapour pressure balance, according to Regulation EC No. 440/2008 Method A.4. Vapour Pressure and OECD Test Guideline 104 (2006).
The vapour pressure of the test item was < 0.02 Pa at 20°C, 25°C and at 50°C.
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