Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 920-008-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to fish, other
- Remarks:
- QSAR
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- October 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This summary has a reliability of 2 because the results are estimated using a computer model that is appropriate for use with this hydrocarbon substance.
- Justification for type of information:
- The aquatic toxicity was estimated by a QSAR, the Petrotox computer model (v 3.06). This model combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The aquatic toxicity was estimated by a QSAR, the Petrotox computer model (v 3.06). This model combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism
- GLP compliance:
- no
- Remarks:
- The data was calculated by a computer model
- Analytical monitoring:
- not required
- Details on sampling:
- No data
- Vehicle:
- no
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- No data
- Test type:
- other: QSAR modelled data
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 28 d
- Post exposure observation period:
- No data
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- Salinity:
- No data
- Nominal and measured concentrations:
- No data
- Reference substance (positive control):
- not required
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOELR
- Effect conc.:
- 0.25 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Details on results:
- No data
- Results with reference substance (positive control):
- No data
- Reported statistics and error estimates:
- No data
- Validity criteria fulfilled:
- yes
- Conclusions:
- The estimated freshwater fish 28-day NOELR (Loewst Observed Effect Loading Rate) value is 0.25 mg/L based on growth.
- Executive summary:
The aquatic toxicity was estimated using the Petrotox computer model, which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism. The estimated freshwater fish 28-day NOELR (Lowest Observed Effect Loading Rate) value is 0.25 mg/L.
- Endpoint:
- fish, juvenile growth test
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- Not applicable, calculated value
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This summary has a reliability of 2 because the results are estimated using a computer model that is appropriate for use with this hydrocarbon substance.
- Justification for type of information:
- Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) straddles Hydrocarbons, C9-C14, Aliphatics, (2-25% Aromatics) and Hydrocarbons, C14-C20, Aliphatics (2-30% Aromatics). Read across justification documents have been provided for the same in Section 13 of the dossier. For this substance, a worst case scenario approach has been used for each endpoint.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Tha aquatic toxicity was estimated by a QSAR, the Petrotox computer model. This model combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partition coefficients (KMW) that describe the partitionning of the hydrocarbons between the water and organism.
- GLP compliance:
- no
- Remarks:
- The data were calculated by a computer model
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No test surrogate nor analogue material - Analytical monitoring:
- not required
- Details on sampling:
- Not applicable (calculated data)
- Vehicle:
- no
- Details on test solutions:
- Not applicable (calculated data)
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- Not applicable (calculated data)
- Test type:
- other: QSAR modeled data
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 28 d
- Post exposure observation period:
- Not applicable (calculated data)
- Hardness:
- Not applicable (calculated data)
- Test temperature:
- Not applicable (calculated data)
- pH:
- Not applicable (calculated data)
- Dissolved oxygen:
- Not applicable (calculated data)
- Salinity:
- Not applicable (calculated data)
- Nominal and measured concentrations:
- Not applicable (calculated data)
- Details on test conditions:
- Not applicable (calculated data)
- Reference substance (positive control):
- no
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOELR
- Effect conc.:
- 0.13 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Details on results:
- No details
- Results with reference substance (positive control):
- No reference substance
- Reported statistics and error estimates:
- Not applicable
- Validity criteria fulfilled:
- yes
- Conclusions:
- The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value is 0.13 mg/l based on growth.
- Executive summary:
The aquatic toxicity was estimated using the Petrotox computer model, which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value is 0.13 mg/l based on growth.
- Endpoint:
- fish, juvenile growth test
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- Not applicable, calculated value
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This summary has a reliability of 2 because the results are estimated using a computer model that is appropriate for use with this hydrocarbon substance.
- Justification for type of information:
- Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) straddles Hydrocarbons, C9-C14, Aliphatics, (2-25% Aromatics) and Hydrocarbons, C14-C20, Aliphatics (2-30% Aromatics). Read across justification documents have been provided for the same in Section 13 of the dossier. For this substance, a worst case scenario approach has been used for each endpoint.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Tha aquatic toxicity was estimated by a QSAR, the Petrotox computer model. This model combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partition coefficients (KMW) that describe the partitionning of the hydrocarbons between the water and organism.
- GLP compliance:
- no
- Remarks:
- The data were calculated by a computer model
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material:
No test surrogate nor analogue material - Analytical monitoring:
- not required
- Details on sampling:
- Not applicable (calculated data)
- Vehicle:
- no
- Details on test solutions:
- Not applicable (calculated data)
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- Not applicable (calculated data)
- Test type:
- other: QSAR modeled data
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 28 d
- Post exposure observation period:
- Not applicable (calculated data)
- Hardness:
- Not applicable (calculated data)
- Test temperature:
- Not applicable (calculated data)
- pH:
- Not applicable (calculated data)
- Dissolved oxygen:
- Not applicable (calculated data)
- Salinity:
- Not applicable (calculated data)
- Nominal and measured concentrations:
- Not applicable (calculated data)
- Details on test conditions:
- Not applicable (calculated data)
- Reference substance (positive control):
- no
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOELR
- Effect conc.:
- 0.091 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Details on results:
- No details
- Results with reference substance (positive control):
- No reference substance
- Reported statistics and error estimates:
- Not applicable
- Validity criteria fulfilled:
- yes
- Conclusions:
- The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value is 0.091 mg/l based on growth.
- Executive summary:
The aquatic toxicity was estimated using the Petrotox computer model, which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value is 0.091 mg/l based on growth.
- Endpoint:
- fish, juvenile growth test
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- Not applicable, calculated value
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This summary has a reliability of 2 because the results are estimated using a computer model that is appropriate for use with this hydrocarbon substance.
- Justification for type of information:
- Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) straddles Hydrocarbons, C9-C14, Aliphatics, (2-25% Aromatics) and Hydrocarbons, C14-C20, Aliphatics (2-30% Aromatics). Read across justification documents have been provided for the same in Section 13 of the dossier. For this substance, a worst case scenario approach has been used for each endpoint.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Tha aquatic toxicity was estimated by a QSAR, the Petrotox computer model. This model combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partition coefficients (KMW) that describe the partitionning of the hydrocarbons between the water and organism.
- GLP compliance:
- no
- Remarks:
- The data were calculated by a computer model
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No test surrogate nor analogue material - Analytical monitoring:
- not required
- Details on sampling:
- Not applicable (calculated data)
- Vehicle:
- no
- Details on test solutions:
- Not applicable (calculated data)
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- Not applicable (calculated data)
- Test type:
- other: QSAR modeled data
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 28 d
- Post exposure observation period:
- Not applicable (calculated data)
- Hardness:
- Not applicable (calculated data)
- Test temperature:
- Not applicable (calculated data)
- pH:
- Not applicable (calculated data)
- Dissolved oxygen:
- Not applicable (calculated data)
- Salinity:
- Not applicable (calculated data)
- Nominal and measured concentrations:
- Not applicable (calculated data)
- Details on test conditions:
- Not applicable (calculated data)
- Reference substance (positive control):
- no
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOELR
- Effect conc.:
- 0.079 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Details on results:
- No details
- Results with reference substance (positive control):
- No reference substance
- Reported statistics and error estimates:
- Not applicable
- Validity criteria fulfilled:
- yes
- Conclusions:
- The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value is 0.079 mg/l based on growth.
- Executive summary:
The aquatic toxicity was estimated using the Petrotox computer model, which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value is 0.079 mg/l based on growth.
- Endpoint:
- adult fish: sub(lethal) effects
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 9-Oct-2001 to 30-Oct-2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The study was given a reliability rating of 1 because it followed a standard test guideline, which describes a procedure to evaluate this endpoint, and the results were reviewed for reliability and assessed as valid. The study was also conducted under GLP.
- Justification for type of information:
- Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) straddles Hydrocarbons, C9-C14, Aliphatics, (2-25% Aromatics) and Hydrocarbons, C14-C20, Aliphatics (2-30% Aromatics). Read across justification documents have been provided for the same in Section 13 of the dossier. For this substance, a worst case scenario approach has been used for each endpoint.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study)
- Deviations:
- yes
- Remarks:
- Deviations did not impact the validity of the study.
- Principles of method if other than guideline:
- Study duration 21 days instead of 14 days as suggested by test guideline.
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- Samples were removed from the control and 2500 and 5000 mg/l concentrations on Day 0, 7, 14, and 21 of the study.
- Vehicle:
- no
- Details on test solutions:
- Test solutions were prepared as Water Accommodated Fractions (WAF). The test substance was added to test water, and stirred for 23 hours with a magnetic stirrer until equilibrium. The mixing was done at a slow enough speed as to not cause dispersion or emulsification of the undissolved test substance. The solution was allowed to stand for approximately 1 hour, to allow phase separation, before being carefully siphoned out via a glass tube (added prior to the addition of the test substance). Renewal of the test WAF was conducted every 24 hours.
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Brachydanio rerio (Teleostei, Cyprinidae)
Source of supply - MPI Tubingen
Pre-treatment - the animals were held for >12 days, <5% mortality
(light/dark = 14h / 10h; illumination: GroLux fluorescent tubes).
The animals were 3.0 to 3.5 cm in size. - Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 21 d
- Test temperature:
- 20.7 to 23.7 dec C
- pH:
- 8.3 to 8.5
- Dissolved oxygen:
- >75%
- Salinity:
- freshwater
- Nominal and measured concentrations:
- Nominal concentrations were: 0, 2500, 5000 mg/l.
Concentration analysis (TOC) of the control and 2500 and 5000 mg/l test concentrations gave results of <10 mg/l. Indicating very low solubility of the test substance. - Details on test conditions:
- 10 animals/conc.
20 L glass aquaria with aeration via glass pipette.
14h light / 10h dark.
Animals were fed 1 time per day - Reference substance (positive control):
- no
- Key result
- Duration:
- 21 d
- Dose descriptor:
- LL50
- Effect conc.:
- > 5 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Key result
- Duration:
- 21 d
- Dose descriptor:
- NOELR
- Effect conc.:
- 5 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- Percent Mortality: (at end of test)
Control - 0%
2500 mg/l - 0%
5000 mg/l - 0% - Validity criteria fulfilled:
- yes
- Conclusions:
- The chronic toxicity of Hydrocarbons, C11 -C20, n-alkanes, isoalkanes, cyclics, aromatics (2 -30%) as measured by toxicity to the zebrafish (Brachydanio rerio) was evaluated in freshwater. Hydrocarbons, C11 -C20, n-alkanes, isoalkanes, cyclics, aromatics (2 -30%) did not show toxic effects as a Water Accommodated Fraction (WAF) with a 21 -day LL50 of >5000 mg/l and is not chronically toxic to fish.
- Executive summary:
The chronic toxicity of Hydrocarbons, C11 -C20, n-alkanes, isoalkanes, cyclics, aromatics (2 -30%) as measured by toxicity to the zebrafish (Brachydanio rerio) was evaluated in freshwater. Hydrocarbons, C11 -C20, n-alkanes, isoalkanes, cyclics, aromatics (2 -30%) did not show toxic effects as a Water Accommodated Fraction (WAF) with a 21 -day LL50 of >5000 mg/l and is not chronically toxic to fish.
Referenceopen allclose all
The composition used to run the Petrotox model is below, derived from the boundary compositions in the SIP for the substance;
Carbon Number | n-P | i-P | i-N | MoAr |
10 | 1.593 | 1.593 | 1.593 | 0.098 |
11 | 2.007 | 2.007 | 2.007 | 0.123 |
12 | 3.388 | 3.388 | 3.388 | 3.388 |
13 | 3.613 | 3.613 | 3.613 | 3.613 |
14 | 5.902 | 5.902 | 5.902 | 0.361 |
15 | 4.426 | 4.426 | 4.426 | 0.271 |
16 | 4.426 | 4.426 | 4.426 | 0.271 |
17 | 2.715 | 2.715 | 2.715 | 0.166 |
18 | 0.188 | 0.188 | 0.188 | 0.012 |
19 | 0.188 | 0.188 | 0.188 | 0.012 |
20 | 0.188 | 0.188 | 0.188 | 0.012 |
21 | 0.188 | 0.188 | 0.188 | 0.012 |
22 | 0.188 | 0.188 | 0.188 | 0.012 |
23 | 0.188 | 0.188 | 0.188 | 0.012 |
24 | 0.188 | 0.188 | 0.188 | 0.012 |
25 | 0.188 | 0.188 | 0.188 | 0.012 |
26 | 0.188 | 0.188 | 0.188 | 0.012 |
27 | 0.188 | 0.188 | 0.188 | 0.012 |
28 | 0.188 | 0.188 | 0.188 | 0.012 |
29 | 0.188 | 0.188 | 0.188 | 0.012 |
30 | 0.188 | 0.188 | 0.188 | 0.012 |
No other information
No other information
No other information
Description of key information
There is no experimental data available for Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, 2-25% aromatics. Data is read across from structural analogues such as Hydrocarbons, C9-C14 aliphatics, 2-25% aromatics and Hydrocarbons, C14-C20 aliphatic, 2-30% aromatics. Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) straddles Hydrocarbons, C9-C14, Aliphatics, (2-25% Aromatics) and Hydrocarbons, C14-C20, Aliphatics (2-30% Aromatics). Read across justification documents have been provided for the same in Section 13 of the dossier. For this substance, a worst case scenario approach has been used for each endpoint.
Petrotox has been run for the substance.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value for Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) determined using the Petrotox computer model (CONCAWE, 2010) is 0.25 mg/L with rainbow trout, Oncorhynchus mykiss, based on growth.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value for Hydrocarbons, C9-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) is 0.13 mg/L based on growth.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value for Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) is 0.091 mg/L based on growth.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value for Hydrocarbons, C11 -C14, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) is 0.079 mg/L based on growth.
Hydrocarbons, C11-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30%) did not cause toxicity to fish in a 21-day toxicity study with Brachydanio rerio following standard test guidelines at a nominal loading of 5000 mg/L. These results indicate that hydrocarbons, C11-C20, n-alkanes, isoalkanes, cyclics, aromatics ( -30%) is not expected to be chronically toxic to fish.
These data are used as read across data for Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, 2-25% aromatics.
Key value for chemical safety assessment
Additional information
The aquatic toxicity was estimated using the Petrotox computer model (v. 3.04), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value for Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) is 0.25 mg/L based on growth.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value for Hydrocarbons, C9-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) is 0.13 mg/L based on growth.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value for Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) is 0.091 mg/L based on growth.
The estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value for Hydrocarbons, C11 -C14, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) is 0.079 mg/L based on growth.
Hydrocarbons, C11-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30%) did not cause toxicity to fish in a 21-day toxicity study with Brachydanio rerio following standard test guidelines at a nominal loading of 5000 mg/L. These results indicate that hydrocarbons, C11-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30%) is not expected to be chronically toxic to fish.
These data are used as read across data for Hydrocarbons, C12-C16, n-alkanes, isoalkanes, cyclics, 2-25% aromatics.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

EU Privacy Disclaimer
This website uses cookies to ensure you get the best experience on our websites.