Registration Dossier
Registration Dossier
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EC number: 224-338-5 | CAS number: 4316-73-8
Endpoint summary
Administrative data
Description of key information
The substance is a strong base (pH > 11.5) and there is reliable in vitro data available from an in vitro study indicating that sodium sarcosinate is corrosive.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
The substance is a strong base (pH > 11.5) and there is reliable data available from an in vitro study indicating the potential to cause skin corrosion. Consequently, it is assumed that the substance has a potential to cause serious eye damage as well. Due to the availiable informatin no in vivo testing with the strong base is warranted.
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: corrosive
Justification for classification or non-classification
Despite the lack of an in vivo study, there is sufficient indication based on pH value and in vitro data to warrant classification for skin corrosion. Residual concentration of NaOH is well below the classification threshold for Skin Corrosion Category 1A according to the CLP regulation (EC) 1272/2008. Since no distinction between Category 1B and 1C can be made, the substance is classified for category 1B. Consequently, the substance is classified as Corrosive and labelled C, R34 according to 67/548/EEC.
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