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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: method close to the method for water solubility, without GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

Principles of method if other than guideline:
Similar to the EU-method for determination of the water solubility.
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
1,3,5-triazine-2,4,6triamine-N-(4,6-diamino-1,3,5triazine-2-yl)
IUPAC Name:
1,3,5-triazine-2,4,6triamine-N-(4,6-diamino-1,3,5triazine-2-yl)
Constituent 2
Reference substance name:
melam
IUPAC Name:
melam
Details on test material:
Purity: 99.6 %.

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
methanol
Solubility:
0.174 mg/L
Temp.:
23 °C
Remarks on result:
other: mean of 0.172 and 0.176 mg/L
Test substance stable:
not determined

Applicant's summary and conclusion

Conclusions:
The solubility of melam in methanol at 23.0 ºC is 0.174 mg/l.
Executive summary:

The solubility of melam in methanol HPLC grade at 23.0 ºC is 0.174 mg/l.