Registration Dossier

Administrative data

Description of key information

Melam is of low  toxicity for each of the exposure routes.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
5 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
5 264 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 500 mg/kg bw

Additional information

The LD50s are greater than the figures forced in the field "Value used for CSA", but cannot be entered as relative results (e.g. >5000 mg/kg bw).

Justification for classification or non-classification

The LD50 respectively LC50 are clearly above the threshold of classification.