Registration Dossier
Registration Dossier
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EC number: 426-040-2 | CAS number: 25713-60-4 SR-245
Endpoint summary
Administrative data
Description of key information
Acute Oral and Acute dermal toxicity studies.
Acute inhalation study is waived based on low hazard and low risk
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
Acute oral and dermal toxicity studies were performed in male and female rats with FR-245. No mortalities were observed in either sex at 2000 mg/kg following oral administration. No mortalities were observed in either sexes following dermal application of 2000 mg/kg. No signs of systemic toxicity were noted during clinical observations in both studies. No abnormalities were noted during necropsy in both studies. FR-245 is not classified for acute oral or dermal toxicity.
Justification for classification or non-classification
Based on the experimental results of the Acute Oral and Dermal toxicity studies (LD<2000),
FR-245 is not classified for acute toxicity.
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