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Toxicological information

Repeated dose toxicity: other routes

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Administrative data

Endpoint:
chronic toxicity: other route
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Experimental derivation of maximum permissible concentrations of isophthaloyl chloride in water reservoirs
Author:
Devyatka DG, Stepanyuk GL, Pushkar MS, Makats VG, Rybak PG, Vashchuk AA, Govachuk GP, and Korolik AG
Year:
1982
Bibliographic source:
Gig. Sanit., (7):75-78 (CA97:121516j)

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Isophthaloyl dichloride
EC Number:
202-774-7
EC Name:
Isophthaloyl dichloride
Cas Number:
99-63-8
Molecular formula:
C8H4Cl2O2
IUPAC Name:
isophthaloyl dichloride
Details on test material:
Isophthaloyl chloride, purity not reported

Results and discussion

Results of examinations

Details on results:
Chronic experiments showed that the minimum acting dose was 2.36 mg/kg and maximum nonacting dose was 1.18 mg/kg.

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion