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Diss Factsheets
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EC number: 202-969-7 | CAS number: 101-72-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
N-isopropyl-N'-phenyl-p-phenylenediamine has an adsorption coefficient in the range of LogKoc = 2.39 to 3.64 (Allmendinger 2015a), however is the substance hydrolytically unstable (half-life 3.9 h). 4-Hydroxydiphenylamine (CAS 122-37-2) is the main hydrolysis product. The estimated LogKoc values for 4-hydroxydiphenylamine, using different accepted calculation methods are in the range of 2.41 to 3.03 (Allmendinger 2015b).
The calculated logKoc value from IPPD, is used for the calculation of PNEC concentration for sediment and soil. The lowest Log Koc of the parent substance was chosen as it represent the worst case (gives the highest PNEC in soil and sediment, calculated by EPM)
The calculated Henry's law constant of 0.000146 Pa m³/mol at 25 °C indicates that the compound has only a limited potential for volatilization from surface waters.
The distribution of N-isopropyl-N'-phenyl-p-phenylenediamine in the environment was calculated according to the Mackay fugacity model level I (Allmendinger 2015 d) based on the physico-chemical properties. The main target compartment for N-isopropyl-N'-phenyl-p-phenylenediamine is water with about 88%, followed by soil and sediment with each about 4 %.
A MacKay level III fugacity model (Robertson 2000, presented in the SIDS report) yielded a more detailed description of the substance in the different compartments: The results show that IPPD released via the water phase leads to negligible exposure of the sediment (0.1%) and to no exposure to soil. Released directly to soil will not result in any significant percentages in sediment. It should be mentioned here that direct release to water and soil are the main routes for environmental exposure, concerning manufacture and DU uses as well as the release from tyres.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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