Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 220-767-7 | CAS number: 2893-78-9
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Several studies acute oral and dietary studies are available in birds with NaDCC and CYA
Key value for chemical safety assessment
Additional information
NaDCC:
Acute oral studies:
In a study with mallard ducks (Fink 1979) birds were given 398, 631, 1000, 1590 and 2510 mg/kg of the test substance. Dieldrin was used as a positive control. The acute oral toxicity LD50 was 1916 mg/kg. In another acute oral study (Robaidek 1985) bobwhite quail were given 633, 844, 1125, 1500 and 2000 mg/kg.of sodium dichloroisocyanurate dihydrate. The LD50 was 1766 mg/kg. In a study with mallard ducks (Robaidek 1984) birds were given 1250, 2500 and 5000 ppm (nominal) of sodium dichloroisocyanurate dihydrate. The dietary LC50 was considered > 5000 ppm.
Dietary studies:
In an eight day dietary study with mallard duck (Fink 1975) Mallard duck were exposed to dietary concentrations of 464, 1000, 2150, 4640 and 10 000 ppm ACL 60 for 5 days. Positive control birds received dietary concentrations of 68, 100, 147, 215 and 316 ppm dieldrin. Negative control birds received the basal diet only. The LC50 was determined to be > 10 000 ppm.
In another dietary study (Fink 1975) bobwhite quail were exposed to dietary concentrations of 464, 1000, 2150, 4640 and 10 000 ppm ACL 60 for 5 days. Positive control birds received dietary concentrations of 10.0, 14.7, 21.5, 31.6 and 46.4 ppm dieldrin. Negative control birds received the basal diet only. The LC50 was determined to be > 10000 ppm.
CYA:
Mallard ducks were exposed to 464, 1000, 2150, 4640 and 10000 ppm nominal concentrations for 5 days and then observed for an additional three days. Negative controls were exposed to a basal diet only. Monosodium cyanurate did not cause any symptoms of toxicity or behavioural abnormalities at the dosage levels tested. There was no mortality at any dosage level, with the exception of an incidental death in the 2150 ppm dosage level. In another study bobwhite quail were exposed to 464, 1000, 2150, 4640 and 10000 ppm dietary concentrations of monosodium cyanurate for 5 days and then observed for an additional three days. Negative controls were exposed to a basal diet only. Monosodium cyanurate did not cause symptoms of the toxicity or behavioural abnormalities at the dosage levels tested. There was no mortality at any dosage level.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
