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Diss Factsheets
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EC number: 203-845-5 | CAS number: 111-20-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Sediment toxicity
Administrative data
Link to relevant study record(s)
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: OSPAR Protocols on Methods for the Testing of Chemicals Used in the Offshore Oil Industry. OSPAR Commission 2005. PartA: A Sediment Bioassay Using an Amphipod Corophiumsp.
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on sediment and application:
- - Natural sediment with organic content of 2.1 % and silt fraction of 68 %.
- The sediment was homogenized before preparing the test sediment.
- Each test concentration was prepared separately.
- The appropriate amount of test substance w as dissolved in about 5 mL of acetone.
- This solution w as added to app. 90 g of predried sediment.
- After the acetone had dried off in a fume cupboard, the sample w as added to app. 500 g of damp sediment in a plastic bucket.
- 130-150 mL of seawater was added to each buckets and the buckets w ere shaken (100 rpm) for about 24 hours.
- The sediment w as split into three beakers, 400 mL of seawater w as added to each.
- The beakers w ere aerated over night in a climate controlled room with 15 °C. - Test organisms (species):
- Corophium volutator
- Details on test organisms:
- - The Corophium volutator used in the test were collected 21.10.2009 b y Biotix (Dag Altin), Trondheim, Norway.
- The organisms w ere transported by car and airplane to Eurofins on 26.10.09.
- At Eurofins they were held at a temperature of 15.0-16.4 °C.
- The amphipods were 5 - 10 mm long. - Study type:
- laboratory study
- Test type:
- static
- Water media type:
- saltwater
- Type of sediment:
- natural sediment
- Limit test:
- no
- Duration:
- 10 d
- Exposure phase:
- total exposure duration
- Test temperature:
- 14.4-15.8 °C
- pH:
- initial 8.0-8.1
- Dissolved oxygen:
- Initial: 92-97 % saturation
After 5d: 91-98 % saturation
After 10d: 90-96 % saturation - Salinity:
- 34.4 per mill
- Nominal and measured concentrations:
- - Test concentrations nominal: 58, 99, 181 and 340 mg / kg sediment (dry weight)
- Details on test conditions:
- TEST SYSTEM
- The test was run in 600 mL glass containers.
- Four concentrations of reference substance were prepared: 5.6, 10.3. 18.0 and 32.2 mg / kg sediment (dry weight)
- Three replicates each containing app. 200 g of test sediment and app. 400 ml seawater was prepared for each concentration.
- Six glass containers served as blanks. Three of them were added acetone.
- 10 test organisms were added to each glass container.
TEST MEDIUM / WATER PARAMETERS
- Natural seawater from an unpolluted site at about 80 m depths in Byfjord was collected from a tap.
- Natural sediment from the same unpolluted site as the amphipod was collected and used for the test.
EFFECT PARAMETERS MEASURED
- After sieving with a mesh size of 0.5 mm the lethality was registered by visual observation.
- Measurement of salinity, oxygen, temperature and pH were done at start, after five and after ten days. - Reference substance (positive control):
- yes
- Remarks:
- Fluoranthene
- Duration:
- 10 d
- Dose descriptor:
- LC50
- Effect conc.:
- 161 mg/kg sediment dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- Dicarboxylic acid:
LC10 10d 39 mg/kg sediment dw
LC90 10d >340 mg/kg sediment dw - Results with reference substance (positive control):
- Floranthene:
LC10 10d 7.3 mg/kg sediment dw
LC50 10d 12 mg/kg sediment dw
LC90 10d 19.7 mg/kg sediment dw
NOEC 10d 5.6 mg/kg sediment dw - Endpoint:
- sediment toxicity: long-term
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Referenceopen allclose all
Description of key information
No risk for sediment organisms is expected due to lacking adsorptive and bioaccumulative properties of the substance and missing distribution into sediment. Hence, information about effects on sediment organisms is not required.
Key value for chemical safety assessment
Additional information
No risk for sediment organisms is expected due to lacking adsorptive and bioaccumulative properties of the substance and missing distribution into sediment. Hence, information about effects on sediment organisms is not required.
Nevertheless, the toxicity on sediment organisms was tested with the marine amphipod Corophium volutator, in accordance with the OSPAR Protocols on methods for testing of chemicals used in the offshore oil industry [BASF SE, 2009]. The 10 days LC50 was 161 mg/kg sediment dry weight.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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