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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Chloromethane  is gaseous and the primary environmental compartment to which it partition is air. The substance is not harmful to invertebrates.

Key value for chemical safety assessment

Additional information

Chloromethane is a gaseous substance and primary environmental compartment to which it partition is air. Therefore, thesubstance will evaporate from the water body. As such significant toxicological effects on aquatic organisms are not expected.

One reliable Daphnia magna study from DOW (2000) according to OECD 202 is available and was conducted under static-renewal test conditions (renewal at 24h) in a closed (no headspace) system and analysis of exposure solutions following 24 hours of aging in closed vessels without headspace showed little to no loss of test substance. This studies indicate chloromethane is of low toxicity to Daphnia magna (EC50 = 200 mg/L) and the reported results are comparable to the 48-h LC50 of 394 mg/L for daphnia predicted by ECOSAR. The ECOSAR model is a reliable and valid QSAR model to apply to chloromethane because it is based on a related chemical dataset. All data show toxicities of chloromethane far in excess of natural occurring concentrations. The substance is not harmful to invertebrates.