Glycerides, tallow sesqui-, hydrogenated, propoxylated

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

07 December 2015 - 26 July 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Specific details on test material used for the study:

Identity: RM1006114
Appearance: White creamy solid (at 20°C)
Storage conditions: Room temperature (15 to 25°C)
Batch number: RL 686/15
Purity: 100%
Expiry date: 30 October 2018
Date received: 12 November 2015

Key result

Water solubility:

< 8 mg/L

Conc. based on:

test mat.

Loading of aqueous phase:

100 other: ml

Incubation duration:

> 1 - < 3 d

Temp.:

20 °C

Remarks on result:

other: pH not specified

Details on results:

Results of the test and show water solubility values of approximately 8 and 49 mg/L at the low and high test loadings respectively.
The increase in solubility with loading indicated that minor impurities are likely to have contributed significantly to these values. Based on structure, the solubility of the test item itself was anticipated to be much lower. Computer modelling ((WSKOWWIN, Version 1.42, U.S. Environmental Protection Agency) indicated a water solubility of much less than 1 mg/l for RM1006114. The solubility value of 8 mg/L should be considered to be a maximum value.

Conclusions:

The water solubility of the substance was evaluated in accordance with EU Method A.6 and OECD Guideline 105 via a GLP-certified laboratory. Analysis via Total Carbon Content determined the water solubility to be < 8 mg/L.

Executive summary:

The water solubility of the substance was evaluated in accordance with EU Method A.6 and OECD Guideline 105 via a GLP-certified laboratory.

Results of the test and show water solubility values of approximately 8 and 49 mg/L at the low and high test loadings respectively.

The increase in solubility with loading indicated that minor impurities are likely to have contributed significantly to these values. Based on structure, the solubility of the test item itself was anticipated to be much lower. Computer modelling ((WSKOWWIN, Version 1.42, U.S. Environmental Protection Agency) indicated a water solubility of much less than 1 mg/l for RM1006114. The solubility value of 8 mg/L should be considered to be a maximum value.

Analysis via Total Carbon Content determined the water solubility to be < 8 mg/L.

Description of key information

The water solubility of the substance was evaluated in accordance with EU Method A.6 and OECD Guideline 105 via a GLP-certified laboratory.

Results of the test and show water solubility values of approximately 8 and 49 mg/L at the low and high test loadings respectively.

The increase in solubility with loading indicated that minor impurities are likely to have contributed significantly to these values. Based on structure, the solubility of the test item itself was anticipated to be much lower. Computer modelling ((WSKOWWIN, Version 1.42, U.S. Environmental Protection Agency) indicated a water solubility of much less than 1 mg/l for RM1006114. The solubility value of 8 mg/L should be considered to be a maximum value.

Analysis via Total Carbon Content determined the water solubility to be < 8 mg/L.

Key value for chemical safety assessment

Water solubility:

8 mg/L

at the temperature of:

20 °C