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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Description of key information

In a GLP study conducted according to OECD Guideline 207, the 14-d LC50, LC0 and LC100 (survival) of trisodium EDDS to the earthworm, Eisenia fetida, were calculated to be 115, 10 and 1000 mg/kg dry soil, respectively. Further, the 14-d NOEC for survival, appearance, behaviour and weight loss was 32 mg/kg dry soil.

Key value for chemical safety assessment

Short-term EC50 or LC50 for soil macroorganisms:
115 mg/kg soil dw

Additional information

A GLP study was conducted according to OECD Guideline 207 to determine the short-term toxicity of trisodium EDDS to the earthworm, Eisenia fetida. Worms were exposed to trisodium EDDS (in water), mixed with an artificial soil, at nominal concentrations of 0, 10, 32, 100, 320 and 1000 mg/kg dry soil, and observed for survival, appearance and behaviour after 7 and 14 days of exposure. Mortality at the end of exposure period (Day 14) was 0/40, 0/40, 1/40, 21/40, 34/40 or 40/40 at 0, 10, 32, 100, 320 or 1000 mg/kg dry soil, respectively. Survival was statistically significantly reduced compared to controls at 100 mg/kg dry soil and above. Surviving worms were observed to be slower at concentrations of 100 and 320 mg/kg dry soil. Average weight losses were 10.5, 10.4, 14.6, 24.7, 20.4 or 100% at 0, 10, 32, 100, 320 or 1000 mg/kg dry soil, respectively. In conclusion, 14-d LC50, LC0 and LC100 of trisodium EDDS to Eisenia fetida were calculated to be 115, 10 and 1000 mg/kg dry soil, respectively. Further, the 14-d NOEC for survival, appearance, behaviour and weight loss was 32 mg/kg dry soil (Henzen, 1999a).

[Data on trisodium EDDS is considered relevant to use for understanding the potential toxicity to earthworms of EDDS acid, and is acceptable for using as read-across information.]