Registration Dossier
Registration Dossier
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EC number: 204-648-7 | CAS number: 123-75-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The biodegradability of Pyrrolidine was investigated in a non-GLP test according to OECD guideline 301E using non-adapted
domestic activated sludge as inoculum (BASF SE, 1991). After 9 days a degradation rate of 94.7% was measured related to the removal of dissolved organic carbon (DOC). Hence, the substance is readily biodegradable according to OECD criteria.
A BOD5/COD test was carried out according to "Bepaling van potentiële milieu-effecten in het water van chemicalien en afvalwater. Deel 2 TNO 1977" and NEN 3235 -5.3 (DSM, 1984). From the biodegradation study it can be concluded that pyrrolidine is readily biodegradable (83 % biodegradation within 5 days). Two studies from Heide-Haugmo et al. 2009 & 2009 according to OECD 306 with marine water support this conclusiong also for marine conditions.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The biodegradability of Pyrrolidine was investigated in four studies:
- a non-GLP test according to OECD guideline 301E using non-adapted domestic activated sludge as inoculum (BASF SE, 1991);
- a BOD5/COD test was carried out according to "Bepaling van potentiële milieu-effecten in het water van chemicalien en afvalwater. Deel 2 TNO 1977" and NEN 3235 -5.3 (DSM, 1984).
- two non-GLP tests according to OECD 306 (seawater) by Eide-Haugmo et al. 2009 and 2012
The study conducted by BASF (1991) was chosen as the key study since it was performed according to OECD guideline 301E.
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