Registration Dossier
Registration Dossier
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EC number: 260-375-3 | CAS number: 56773-42-3
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Adsorption/desorption behaviour of a read-across substance (CAS no. 2795-39-3, Potassium perfluorooctanesulfonate) was determined according to OECD 106 (Equilibrium batch method) and is given as Koc = 0.0374 with clay loam, 0.0571 with river sediment, 0.0704 with clay and 0.126 L/kg with sandy loam (Ellefson 2010).
Key value for chemical safety assessment
Additional information
Read-across justification
- Group: Tetraethylammonium heptadecafluorooctanesulphonate (56773-42-3) and Potassium perfluorooctanesulfonate (CAS no. 2795-39-3)
- Justification: REACH regulation EC 1907/2006 and ECHA guidance document R.6 give that substances whoses physicochemical, toxicological and ecotoxicological properties are likely to be similar, or follow a regular pattern as a result of structural similarity, may be considered as a group / category of substances.
- Chemical similarity: According to OECD, 2002, (ENV/JM/RD(2002)17/FINAL) “perfluorinated compounds represent a very unique chemistry”, at least substances with equal numbers of perfluorinated carbon atoms and functional groups. The “Environmeltal Risk Evaluation Report” of Brooke et al., 2004, (Environment Agency, GB) differentiated perfluorinated substances in groups with PFOS itself being a group, consisting of salts with e.g. potassium and ammonium (including quartenary ammonium) as counter ion. Thus, in accordance with OECD, 2002, grouping and read-across based on the length of the perfluorinated C8 structure with a sulfonate moiety is very well justified. Furthermore, Brooke et al. gave that the C8 structure with sulfonate ending is negatively charged being opposed by a positively charged counter ion that might be potassium or tetraethylammonium. The substance which is used for read-across is potassium perfluorooctanesulfonate which consists of a C8 structure, a sulfonate moiety and the counter ion potassium. Thus, the criterion of structural similarity is fulfilled.
- Physical behaviour: Both substances are organic salts which show surface activity and ionic properties which make it impossible to determine partition coefficient (QSAR estimations are possible). The melting and boiling point of both substances are high and both are readily dissolvable in water. Thus, physicochemical porperties are also similar.
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