Registration Dossier
Registration Dossier
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EC number: 260-375-3 | CAS number: 56773-42-3
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
These results show that the test item tetraethylammonium perfluorooctane sulfonate has no sensitizing potential in mice after dermal application of up to and including a 50% concentration. No indication for a non-specific (irritant) activation was detected, too. Therefore, the concentration of 50% turned out to be the NOEL for the parameters investigated in this study with respect to skin sensitization.
Migrated from Short description of key information:
The modified Local Lymph Node Assay (IMDS) was performed on 24 female NMRI mice of the strain Crl:NMRI Br (6 animals/test item group and 6 control animals) to determine if the is any specific (sensitizing) or non-specific (irritant) stimulating potential of the test item tetraethylammonium perfluorooctane sulfonate.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
no data
Migrated from Short description of key information:
no data
Justification for classification or non-classification
Due to the results of a LLNA in mice no skin sensitizing potential was found for tetraethylammonium perfluorooctane sulfonate after dermal application of up to and including 50% concentration.
Therefore a classification is not justified.
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