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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
other: QSAR toolbox
Title:
QSAR study for CAS: 371-40-4
Year:
2011
Bibliographic source:
OECD QSAR toolbox version 2.2, 2011:- Phys-chem EPISUITE (SRC); HANSCH,C ET AL. (1995)
Reference Type:
review article or handbook
Title:
Reaxys ID : 742030
Year:
2011
Bibliographic source:
Reaxys by Elsevier Properties SA; Wang, Xiaodong; Sun, Cheng; Gao, Shixiang; Wang, Liansheng; Shuokui, Han; Chemosphere; vol. 44; nb. 3; (2001); p. 1711 - 1722
Reference Type:
review article or handbook
Title:
Dose doc.no.: F60
Author:
RSC Publishing
Year:
2011
Bibliographic source:
Dictionary of Substances and their effects (DOSE);Schultz, T. W. et al Bull. Environ. Contam. Toxicol. 1989, 43(4), 564-569.
Reference Type:
other: Authoritative data base
Title:
HSDB Number: 2691
Year:
2011
Bibliographic source:
HSDB (Hazardous Substances Data Bank); US national Library of Medicine reviewed by SRC:Hansch C, Leo AJ; Medchem (26): (1985)

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Data is taken from OECD QSAR, DOSE, HSDB and Reaxys Database
GLP compliance:
not specified
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
4-fluoroaniline
EC Number:
206-735-5
EC Name:
4-fluoroaniline
Cas Number:
371-40-4
Molecular formula:
C6H6FN
IUPAC Name:
4-fluoroaniline
Details on test material:
- Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
1.15
Temp.:
25 °C
Remarks on result:
other: pH data not available

Applicant's summary and conclusion

Conclusions:
Partition coefficient (log Pow) of octanol-water of 4-fluoroaniline is 1.15
Executive summary:

LogP is the logarithm (base-10) of the partition coefficient between n-octanol and water. It is used in environmental fate studies and large values (+4 or higher) are regarded as an indicator that a substance will bio-accumulate.

Octanol-water partition coefficient (log Pow) of 4-fluoroaniline is 1.15.Based on this, this substance is not likely to bio accumulate in food chain.