Registration Dossier
Registration Dossier
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EC number: 206-735-5 | CAS number: 371-40-4
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- other: QSAR toolbox
- Title:
- QSAR study for CAS: 371-40-4
- Year:
- 2 011
- Bibliographic source:
- OECD QSAR toolbox version 2.2, 2011:- Phys-chem EPISUITE (SRC); HANSCH,C ET AL. (1995)
- Reference Type:
- review article or handbook
- Title:
- Reaxys ID : 742030
- Year:
- 2 011
- Bibliographic source:
- Reaxys by Elsevier Properties SA; Wang, Xiaodong; Sun, Cheng; Gao, Shixiang; Wang, Liansheng; Shuokui, Han; Chemosphere; vol. 44; nb. 3; (2001); p. 1711 - 1722
- Reference Type:
- review article or handbook
- Title:
- Dose doc.no.: F60
- Author:
- RSC Publishing
- Year:
- 2 011
- Bibliographic source:
- Dictionary of Substances and their effects (DOSE);Schultz, T. W. et al Bull. Environ. Contam. Toxicol. 1989, 43(4), 564-569.
- Reference Type:
- other: Authoritative data base
- Title:
- HSDB Number: 2691
- Year:
- 2 011
- Bibliographic source:
- HSDB (Hazardous Substances Data Bank); US national Library of Medicine reviewed by SRC:Hansch C, Leo AJ; Medchem (26): (1985)
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is taken from OECD QSAR, DOSE, HSDB and Reaxys Database
- GLP compliance:
- not specified
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 4-fluoroaniline
- EC Number:
- 206-735-5
- EC Name:
- 4-fluoroaniline
- Cas Number:
- 371-40-4
- Molecular formula:
- C6H6FN
- IUPAC Name:
- 4-fluoroaniline
- Details on test material:
- - Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 1.15
- Temp.:
- 25 °C
- Remarks on result:
- other: pH data not available
Applicant's summary and conclusion
- Conclusions:
- Partition coefficient (log Pow) of octanol-water of 4-fluoroaniline is 1.15
- Executive summary:
LogP is the logarithm (base-10) of the partition coefficient between n-octanol and water. It is used in environmental fate studies and large values (+4 or higher) are regarded as an indicator that a substance will bio-accumulate.
Octanol-water partition coefficient (log Pow) of 4-fluoroaniline is 1.15.Based on this, this substance is not likely to bio accumulate in food chain.
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