Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Currently viewing:

Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: short-term
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
review article or handbook
Title:
Reaxys ID : 742030
Year:
2011
Bibliographic source:
Reaxys by Elsevier Properties SA; Ji, Li; Bundy, Jacob G.; Lenz, Eva M.; Bailey, Nigel J.; et al. ; Environmental Toxicology and Chemistry; vol. 21; nb. 9; (2002); p. 1966 - 1972

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Rapid toxicity test (Organization for Economic and Development):Test material in hexane was applied to the filter paper (52 cm2) and allowed to evaporate; moistened with 1 ml of water; single earthworm placed on to the filter and incubated for 72 h
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-fluoroaniline
EC Number:
206-735-5
EC Name:
4-fluoroaniline
Cas Number:
371-40-4
Molecular formula:
C6H6FN
IUPAC Name:
4-fluoroaniline
Details on test material:
- Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid

Sampling and analysis

Analytical monitoring:
not specified

Test substrate

Vehicle:
not specified

Test organisms

Test organisms (species):
Eisenia sp.
Animal group:
annelids
Details on test organisms:
Test organism: Eisenia veneta, earthworm

Study design

Study type:
laboratory study
Substrate type:
filter paper
Total exposure duration:
72 h

Test conditions

Details on test conditions:
Test material in hexane was applied to the filter paper (52 cm2) and allowed to evaporate; moistened with 1 ml of water; single earthworm placed on to the filter and incubated for 72 h
Nominal and measured concentrations:
25 - 250 μg/cm2

Results and discussion

Effect concentrations
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
115 other: μg/cm2
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Conclusions:
The LC50 (median lethal concentration) value of 4-fluoroaniline to Eisenia veneta (earthworm) during a 72 hr exposure is 115 μg/cm2.
Executive summary:

The LC50 (median lethal concentration) value of 4-fluoroaniline to Eisenia veneta (earthworm) during a 72 hr exposure is 115 μg/cm2.