Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 206-735-5 | CAS number: 371-40-4
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Reaxys ID : 742030
- Year:
- 2 011
- Bibliographic source:
- Reaxys by Elsevier Properties SA; Ji, Li; Bundy, Jacob G.; Lenz, Eva M.; Bailey, Nigel J.; et al. ; Environmental Toxicology and Chemistry; vol. 21; nb. 9; (2002); p. 1966 - 1972
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Rapid toxicity test (Organization for Economic and Development):Test material in hexane was applied to the filter paper (52 cm2) and allowed to evaporate; moistened with 1 ml of water; single earthworm placed on to the filter and incubated for 72 h
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-fluoroaniline
- EC Number:
- 206-735-5
- EC Name:
- 4-fluoroaniline
- Cas Number:
- 371-40-4
- Molecular formula:
- C6H6FN
- IUPAC Name:
- 4-fluoroaniline
- Details on test material:
- - Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test substrate
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Eisenia sp.
- Animal group:
- annelids
- Details on test organisms:
- Test organism: Eisenia veneta, earthworm
Study design
- Study type:
- laboratory study
- Substrate type:
- filter paper
- Total exposure duration:
- 72 h
Test conditions
- Details on test conditions:
- Test material in hexane was applied to the filter paper (52 cm2) and allowed to evaporate; moistened with 1 ml of water; single earthworm placed on to the filter and incubated for 72 h
- Nominal and measured concentrations:
- 25 - 250 μg/cm2
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- 115 other: μg/cm2
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
Applicant's summary and conclusion
- Conclusions:
- The LC50 (median lethal concentration) value of 4-fluoroaniline to Eisenia veneta (earthworm) during a 72 hr exposure is 115 μg/cm2.
- Executive summary:
The LC50 (median lethal concentration) value of 4-fluoroaniline to Eisenia veneta (earthworm) during a 72 hr exposure is 115 μg/cm2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
