Registration Dossier

Diss Factsheets

Administrative data

Description of key information

For workers on manufacturing plant personnel:

The past and ongoing medical investigation provides no evidence of substance-induced health effects, in particular by repeated inhalation or skin contact.

For applicants:

Values for inhalable dusts are below the limits of 10 mg/m³

Values for respirable dust are below the limits of 5 mg/m³ with exception for the mixers.

Values for respirable quartz are below the limits of 75 µg/m³


Oral route:

No significant increased renal excretion of SiO2 after oral uptake resp. no significant oral absorption.

Additional information

No poisoning incidents with substance are known, the substance is used in industrial settings for several decades. This is also supported by the attached medical statement. Here the investigations could not detect any health effects by repeated inhalation or skin contact during production and bagging.