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EC number: 200-746-9 | CAS number: 71-23-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
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- Auto flammability
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- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
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- Additional physico-chemical information
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- Nanomaterial aspect ratio / shape
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- Nanomaterial surface chemistry
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- Nanomaterial pour density
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- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No experimental data for 1-propanol. A QSAR-study conducted with accepted calculation method (OECD QSAR Toolbox v4.2)revealed no reproductive effects at concentration of 68 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 68.3 mg/L
Additional information
The hazard assessment of Propan-1 -ol reveals neither a need to classify the substance as dangerous to the environment, nor PBT or vPvB properties. Concerning long-term toxicity to aquatic invertebrates there are no further indications that the substance may be hazardous to the environment. A QSAR-study conducted with the OECD QSAR Toolbox v4.2 (trend analysis within category members) reveals no reproduction effects to Daphnia magna at a concentration of 68.3 mg/L. The very low chronic toxicity of propan-1 -ol to aquatic invertebrates is supported by the result of a study on the chonic toxicity of the structurally related substance 2 -Propanol (CAS: 67-63-0) to Daphnia magna (performed according to OECD guideline 211 under GLP conditions), where no reproductive effects were observed at concentrations up to 100 mg/l (NOEC > 100 mg/l). In addition, it is very well known that aliphatic alcohols act by non-specific mode of action (narcotic effect). Bengtsson et al. (Chemosphere, Vol. 13, No. 5/6, pp 613 – 622, 1984) have demonstrated in a study with a series of aliphatic alcohols (C1 – C13) that their toxicity is highly correlated to the number of carbon atoms and that the differences in toxicity for the individual compounds in the series can be explained in terms of differences in lipophilicity. Taking into account that propan-1-ol and propan-2-ol are both of very low lipophilicity, the result of the long-term study with daphnids on propan-2-ol can be use to support the low chronic toxicity of propan-1-ol towards aquatic invertebrates.
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