Registration Dossier
Registration Dossier
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EC number: 200-746-9 | CAS number: 71-23-8
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
Materials and methods
- Type of study / information:
- This systematic review is based on a PubMed search of articles published between January 2000 and September 2019 in English and German, and a manual search, related to the irritation potential of alcohol-based disinfectants restricted to n-propanol (1-propanol) and its structural isomer isopropanol (isopropyl alcohol, 2-propanol).
- Endpoint addressed:
- skin irritation / corrosion
Test guideline
- Qualifier:
- no guideline required
Test material
- Reference substance name:
- Propan-1-ol
- EC Number:
- 200-746-9
- EC Name:
- Propan-1-ol
- Cas Number:
- 71-23-8
- Molecular formula:
- C3H8O
- IUPAC Name:
- propan-1-ol
Constituent 1
Results and discussion
- Results:
- The systematic review shows that hand disinfectants with n-propanol concentrations of 60%, or certain combinations of propan-1-ol and propan-2-ol showed little to no irritation in intact skin and previously irritated skin.
Applicant's summary and conclusion
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