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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data is from authorative database
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
24hr short term toxicity studies was carried out to test the effects of 1 chloro-3-nitrobenzene.
GLP compliance:
no
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
No data available
Analytical monitoring:
not specified
Details on sampling:
Details on sampling
- Concentrations: 18.8mg/l
Vehicle:
not specified
Details on test solutions:
No data available
Test organisms (species):
Pimephales promelas
Details on test organisms:
TEST ORGANISM
- Common name: Fathead minnow
- Age at study initiation (mean and range, SD): 33 d
- Length at study initiation (length definition, mean, range and SD): Individual lengths and weigNAs of the test fish were not recorded.
- Weight at study initiation (mean and range, SD): the calculated mean weight was 0.148 g.
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
96 h
Post exposure observation period:
No data available
Hardness:
45.3
Test temperature:
23.0 deg. C
pH:
7.5
Dissolved oxygen:
7.0mg/l
Salinity:
Alkalinity: 42.8mg/l
Nominal and measured concentrations:
No data available
Details on test conditions:
No data available
Reference substance (positive control):
not specified
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
18.8 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
- Behavioural abnormalities: Affected fish lost schooling behavior, were hypoactive, NR and lost equilibrium
prior to death.
Results with reference substance (positive control):
No data available
Reported statistics and error estimates:
No data available
Validity criteria fulfilled:
not specified
Conclusions:
Based on mortality the 96hr LC50 was determined to be 18.8mg/l for fathead minnow.
Based on the LC50 value the substance may be classified as aquatic chronic-3.
Executive summary:

Short term toxicity study have been carried out to test the effects of 1 Chloro-3-nitrobenzene on fresh water fish fathead minnow for 96hr.

Based on mortality the 96hr LC50 was determined to be 18.8mg/l for fathead minnow.

Description of key information

Based on mortality the 96hr LC50 was determined to be 18.8 mg/l for fathead minnow.Based on the LC50 value the substance may be classified as aquatic chronic-3.  

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
18.8 mg/L

Additional information

To evaluate toxicity to fish, various experimental studies were performed.Based on the experimental data aquired from various sources following is the discription:

Short term toxicity study have been carried out to test the effects of 1-Chloro-3-nitrobenzene on fresh water fish fathead minnow for 96hr.Based on mortality the 96 hr LC50 was determined to be 18.8 mg/l for fathead minnow.

in another supporting study,Short term toxicity study have been carried out to test the effects of 1-Chloro-3-nitrobenzene on fresh water fish fathead minnow for 24hr.Based on mortality the 24hr LC50 was determined to be 18 mg/l for fathead minnow.

Even though varied results for short term toxicity to fish were available but, based on the effect concentration from both the experimental study report,we can consider that the test chemical is toxic and can be classified as aquatic chronic 3.