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Environmental fate & pathways

Hydrolysis

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Reference
Endpoint:
hydrolysis
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
REPORTING FORMAT FOR THE ANALOGUE APPROACH
Refer to justification attached below
Reason / purpose for cross-reference:
read-across source
Preliminary study:
In none of the buffer solutions at pH 4, 7 and 9 at 50 °C more than 10 % of the test substance hydrolysed within 5 days.
Transformation products:
no
Key result
pH:
4.06
Temp.:
25 °C
DT50:
> 1 yr
Type:
(pseudo-)first order (= half-life)
Remarks on result:
hydrolytically stable based on preliminary test
Key result
pH:
6.97
Temp.:
25 °C
DT50:
> 1 yr
Type:
(pseudo-)first order (= half-life)
Remarks on result:
hydrolytically stable based on preliminary test
Key result
pH:
8.77
Temp.:
25 °C
DT50:
> 1 yr
Type:
(pseudo-)first order (= half-life)
Remarks on result:
hydrolytically stable based on preliminary test
Details on results:
On the basis of the pre-test results and in accordance with the guidances no main test has been performed.
Conclusions:
Available data from Guanidinium carbonate were used to evaluate the hydrolytic stability of Guanidinium thiocyanate.
The hydrolytic stability of Guanidine carbonate (CAS 593-85-1) was invetigated in a study according to the OECD TG 111 protocol.
The GLP-study is considered reliable and conclusive for chemical safety assessment and classification purposes.
The pre-test indicated a half-life at 25 °C of more than one year.
Thus no DT50 was determined and the guanidine kation is considered hydrolytically stable under environmental conditions.

Description of key information

Key value for chemical safety assessment

Half-life for hydrolysis:
1 yr
at the temperature of:
25 °C

Additional information