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Short-term toxicity to aquatic invertebrates

Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the closest read across substances, the short term toxicity on aquatic invertebrate predicted for 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0). Effect concentration i.e EC50 value estimated to be 169.07 mg/l for Daphnia magna for 48 hrs duration. It can be concluded that the 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) IS likely to be not toxic to aquatic invertebrates, hence it can be considered to be “not classified” as per the CLP classification criteria for aquatic environment.

Toxicity to aquatic algae and cyanobacteria

Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the closest read across substances, the toxicity on algae was predicted 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) Effect concentration i.e EC50 value was estimated to be 109.04  mg/l for Scenedesmus sp. for 72 hrs duration. It was concluded that the 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) was likely to be not toxic to aquatic algae, hence it can be considered to be “not Classified” as per the CLP classification criteria for aquatic environment.

Additional information

Short-term toxicity to aquatic invertebrates

Following three studies available for target chemical and read across chemical includes predicted data and experimental data to conclude the aquatic invertebrate the toxicity of 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) is summarized as follows:

Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the closest read across substances, the short term toxicity on aquatic invertebrate predicted for 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0). Effect concentration i.e EC50 value estimated to be 169.07 mg/l for Daphnia magna for 48 hrs duration. It can be concluded that the 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) IS likely to be not toxic to aquatic invertebrates, hence it can be considered to be “not classified” as per the CLP classification criteria for aquatic environment.

The above predicted data is supported by the experimental data of read acoss Benzene-1,2,4-tricarboxylic acid 1,2-anhydride(CAS:552-30-7) indicates that the effective concentration EC50% TO 50% of daphnia magna is > 1000 mg/l. mobility was considered as effect measurement during the test. It can be concluded form the value that the Benzene-1,2,4-tricarboxylic acid 1,2-anhydride is not toxic to the aquatic environment.

Similar experimental study is availabe for another read across Methyl acetate (CAS: 79 -20 -9) from EUROPEAN COMMISSION – European Chemicals Bureau, sussegts that The effective concentration EC50 to 50% of Daphnia magna at 48 hour(s) is 1026.7 mg/l. considering the mobility effect as a measurement. It can be concluded that the Methyl acetate is not toxic to the aquatic environment.

Thus based on the effect concentrations which is in the range 169.07 mg/l to 1026.7 mg/l give the conclusion that test substance 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) was likely to be not toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered to benot classifiedas per the CLP classification criteria.

Toxicity to aquatic algae and cyanobacteria

Following three studies available for target chemical and read across chemical includes predicted data and experimental data to conclude the aquatic invertebrate the toxicity of 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) is summarized as follows:

Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the closest read across substances, the toxicity on algae was predicted 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) Effect concentration i.e EC50 value was estimated to be 109.04  mg/l for Scenedesmus sp. for 72 hrs duration. It was concluded that the 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) was likely to be not toxic to aquatic algae, hence it can be considered to be “not Classified” as per the CLP classification criteria for aquatic environment.

The above predicted data is supported by the experimental data of read acoss Benzene-1,2,4-tricarboxylic acid 1,2-anhydride(CAS:552-30-7) indicates that The effective concentration 50% EC50 to Scenedesmus subspicatus at 96h is > 1000 mg/l. It can be concluded that the Benzene-1,2,4-tricarboxylic acid 1,2-anhydride is not toxic to the aquatic environment.

Similar experimental study is availabe for another read across Methyl acetate (CAS: 79 -20 -9) from EUROPEAN COMMISSION – European Chemicals Bureau, sussegts that The effective concentration EC50 to 50% of Scenedesmus subspicatus at 72 hour(s) is > 120 mg/l. considering the growth rate effect as a measurement. It can be concluded that the Methyl acetate is not toxic to the aquatic environment.

Thus based on the effect concentrations which is in the range 109.04 mg/l to >1000 mg/l give the conclusion that test substance 3-phenylprop-2-en-1-yl propionate (CAS: 103-56-0) was likely to be not toxic to aquatic algae at environmentally relevant concentrations and can be considered to benot classifiedas per the CLP classification criteria.

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