Bis(2-chloroethyl) ether

Density

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Version / remarks:

The densities were determined with water-calibrated specific-gravity bottles.

GLP compliance:

no

Remarks:

pre-GLP

Type of method:

pycnometer method

Specific details on test material used for the study:

TEST MATERIAL
- Name (as cited): 2:2'-Dichlorodiethyl ether
- Purity: not specified

SOURCE OF TEST MATERIAL
- Source: prepared as described by Kamm & Waldo (J. Amer. Chem. Soc., 1921, 43, 2223)
- Purification: repeated fractionation through a Young column

Key result

Type:

relative density

Density:

1.219 other: dimensionless

Temp.:

20 °C

Type:

relative density

Density:

1.213 other: dimensionless

Temp.:

25 °C

Conclusions:

The relative density of Bis(2-chloroethyl) ether was determined to be 1.2192 at 20°C/4°C and 1.2130 at 25°C/4°C.

Executive summary:

The density of Bis(2-chloroethyl) ether was determined using water-calibrated specific-gravity bottles. Density was determined at two temperature (20 and 25°C). The means of at least two determinations, performed with different bottles were recorded for each temperature. The relative density of Bis(2-chloroethyl) ether was determined to be 1.2192 at 20°C/4°C and 1.2130 at 25°C/4°C. The method is similar to OECD Gudeline No. 109 and the study has been subject to peer-review. It is thus considered reliable and has been assigned a reliability score of 2.

Reference 2

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

yes

Remarks:

14-inch hydrometers were used instead of pycnometers

GLP compliance:

no

Remarks:

pre-GLP

Type of method:

pycnometer method

Specific details on test material used for the study:

TEST MATERIAL:
- Name (as cited): Dichloroethyl ether
- Purity: 99%

Type:

relative density

Density:

1.222 other: dimensionless

Temp.:

20 °C

Conclusions:

The relative density of Bis(2-chloroethyl) ether was determined to be 1.222 at 20°C.

Executive summary:

The specific gravity of Bis(2-chloroethyl) ether was measured using 14 -inch hydrometers (accuracy: 0.0001). The method used is similar to the recommended methods described in OECD Guideline No. 109. The relative density of Bis(2-chloroethyl) ether was determined to be 1.222 at 20°C. The publication reports the physical properties of various laquer solvents and does not include a detailed description of the methodology or results. However, the method appears to be similar to guideline and the study has been subject to peer-review (reliability 2).

Reference 3

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

- Principle of test: not specified
- Short description of test conditions: no data available

Specific details on test material used for the study:

TEST MATERIAL:
- Names (as cited): Bis(2-chloroethyl) ether
- Purity: not specified

Type:

relative density

Density:

1.22 other: dimensionless

Temp.:

20 °C

Conclusions:

The relative density of Bis(2-chloroethyl) ether is described to be 1.2199 (20°C/4°C).

Executive summary:

According to this recognised handbook, the relative density of Bis(2-chloroethyl) ether is 1.2199 (20°C/4°C).

Description of key information

Using water-calibrated specific-gravity bottles (method similar to OECD 109), the relative density of 2:2'-Dichlorodiethyl ether was determined to be 1.2192 at 20°C/4°C and 1.2130 at 25°C/4°C.

Key value for chemical safety assessment

Relative density at 20C:

1.219

Additional information

In a published study by Mumford & Philips (J. Chem. Soc., 1950, 75-84), the density of Bis(2-chloroethyl) ether was determined using water-calibrated specific-gravity bottles. Density was determined at two temperature (20 and 25°C). The means of at least two determinations, performed with different bottles were recorded for each temperature. The relative density of Bis(2-chloroethyl) ether was determined to be 1.2192 at 20°C/4°C and 1.2130 at 25°C/4°C. The method is similar to OECD Gudeline No. 109 and the study has been subject to peer-review. It is thus considered reliable and has been assigned a reliability score of 2.

In a published study by Doolittle (Ind. Eng. Chem., 1935, 27(10):1169 -79), the physical properties of various lacquer solvents are provided. The specific gravity of Bis(2-chloroethyl) ether was measured using 14 -inch hydrometers (accuracy: 0.0001), a method similar to OECD Guideline No. 109. The relative density of Bis(2-chloroethyl) ether was determined to be 1.222 at 20°C (relibaility score of 2).

In the CRC Handbook, Bis(2-chloroethyl) ether is described as having a relative density equal to 1.2199 (20°C/4°C). The data originates from a recognised handbook and has been assigned a reliability score of 2.