Registration Dossier
Registration Dossier
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EC number: 207-988-4 | CAS number: 504-29-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Remarks:
- No further details.
- Details on sampling:
- The concentration of the test substance in the test solution was measured at the beginning and the end of the exposure, and the average value was 95 ~ 100 %, based on the set concentration.
- Vehicle:
- not specified
- Test organisms (species):
- Daphnia magna
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 35 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 41 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 48h-EC50 of the test item to daphnia is 35 mg/L.
- Executive summary:
An acute toxicity test was conducted with the test item on Daphnia magna according to the OECD guideline 202 under GLP conditions. The test item concentration was measured at the beginning and at the end of the exposure time, and remained within 95 -100% of the nominal value. The 48 hours EC50 of the test item on daphnia was 35 mg/L, based on the average value of the measured concentration.
Reference
Description of key information
Key study. Method according to the OECD guideline 202, GLP study. The 48 hours EC50 of the test item is 35 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 35 mg/L
Additional information
An acute toxicity test was conducted with the test item on Daphnia magna according to the OECD guideline 202 under GLP conditions. The test item concentration was measured at the beginning and at the end of the exposure time, and remained within 95 -100% of the nominal value. The 48 hours EC50 of the test item on daphnia was 35 mg/L, based on the average value of the measured concentration.
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