Registration Dossier

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Two reliable chronic toxicity studies were identified. The first study by Biesinger and Christensen, 1972 reported a 21d-EC16 of 5.8 mg Ba2+/L (nominal values), which can be used for the estimation of a NOEC-value of 2.9 mg/L (i.e., EC16/2; ECHA-guidance). Re-calculation to BaCl2 resulted in an NOEC of 4.4 mg BaCl2/L.
The second data point was generated for the marine invertebrate Cancer anthonyi (Macdonald et al, 1988). Here, a nominal, 7d-NOEC of 10 mg Ba2+/L was reported, and this is for the endpoint embryonal hatching. Re-calculation to BaCl2 resulted in an NOEC of 15 mg BaCl2/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
4.4 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
15 mg/L

Additional information

According to ECHA guidance on information requirements and CSA, Chapter R.10: Characterisation of dose [concentrations]-response for environment, May 2008, a NOEC can be estimated by dividing a reliable ECXby 2, and this when X is situated between 10 and 20 % effect. The 21d-EC16of 5.8 mg Ba2+/L forDaphnia magna, as reported by Biesinger and Christensen (1972) is in compliance with this criterion. Therefore a NOEC of4.4 mg BaCl2/L (2.9 mg Ba2+/L) could be derived for the freshwater compartment.

ForCancer anthonyi, 24h-acclimated embryo's stripped from the pleopods of ovigerous females were used as test organisms. This type of life-stage is generally considered as the most sensitive one, and a 7 day exposure period combined with the endpoint under consideration (i.e., hatching/development) should therefore result in relevant chronic effects data.