Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-455-5 | CAS number: 107-03-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of propane-1-thiol to algae has been read across from ethanethiol. Effect concentrations for the toxicity of ethanethiol to Pseudokirchneriella subcapitata were: EbC50 72 hr biomass 0.75mg/L; NOECb 0.83 mg/L; EbC10 0.13 mg/L; ErC50 72 hr growth rate 3.0 mg/L; NOECr 0.83 mg/L; ErC10 0.55 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 3 mg/L
Additional information
The toxicity of propane-1-thiol to algae has been read across from ethanethiol. The Thiebaud (2000) study is GLP compliant and has been done to guideline but is not considered to be fully relevant for risk assessment purposes. The test substance was not maintained within 80% of nominal concentrations, so a geometric mean value was calculated using the initial and final concentrations. The NOEC for both biomass and growth rate were determined using a statistical analytical method (Dunnett test), and the EC10 and EC50 were determined by Probit analysis. The EC10 and EC50 for biomass and the EC10 for growth rate were extrapolated below the measured concentrations, and therefore caution should be taken when using these values. Nevertheless, the study has been considered reliable, with a Klimisch score of 2 by the IUCLID dataset 30.09.2009 and is a critical study for the OECD SIDS Initial Assessment Report C2 -C4 Aliphatic Thiols for SIAM 30 (April 2010).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
