Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-289-2
CAS number: -
Control series: An examination of 2000
metaphase complements revealed 12 (0.6%) gap, 14 (0.7%) constriction and
2 (0.1%) chromatid breaks only.
Treated series: The types of chromosome
aberrations at different concentrations and intervals were more or less
similar. The effects could broadly be put into two main categories, on
general morphology and on the individual chromosome.
The effects on the individual chromosome were
manifested as gap, constriction, subchromatid and chromatid breaks and exchange
type ones. Very likely all of them were isochromatid breaks because the same
chromosome sometimes contained another chromatid break. Tissue fixed at one
hour after the treatment had also a good number of chromosomal aberrations.
The effect of AlCl3 on bone marrow chromosomes of mice was, therefore, non-delayed
type and it continued without much change even at 72 hours. The values of
the aberration frequency were not proportional to the different molar solutions
used. However, the use of higher concentration of AlCl3 increased the aberration
frequency to some extent.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again