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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The 96h LC50s values range from 0.23 mg Ni/L to 320 mg Ni/L for freshwater fish species, and from 26.6 mg Ni/L to 350 mg Ni/L  for marine fish species. 
As the PNEC intermittent endpoint is not relevant for the identified processes (see section summary of IUCLID5 chapter 6), no short-term test are used in any PNEC derivation.

Key value for chemical safety assessment

Additional information


From the database of acute toxicity to freshwater fish, there are 31 high quality studies.  This represents 21 different freshwater fish species, dominated by Pimephales promelas, Oncorhynchus mykiss, and Cyprinus carpio.  The 96h LC50s values range from 0.23 mg Ni/L (Pimphales promelas; Hoang et al., 2004) to 320 mg Ni/L (Brachydanio rerio; NiPERA, 1993).  



From the database of acute toxicity to marine fish, there are 4 high quality studies.  This represents 3 different marine fish species.  The 96h LC50s values range from 26.6 mg Ni/L (Atherinops affinis; Hunt et al., 2002) to 350 mg Ni/L (Fundulus heteroclitus; Eisler and Hennekey, 1977).