Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 5413-60-5
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- EPI Suite (DERMWIN) Various versions of EPI Suite dating back from 1990-2004.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
EPI Suite (DERMWIN)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
EC Number:
226-501-6
EC Name:
3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
Cas Number:
5413-60-5
Molecular formula:
C12H16O2
IUPAC Name:
3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
Details on test material:
- Name of test material (as cited in study report): 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- Substance type: Organic
- Physical state: Liquid
Radiolabelling:
not specified

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Percutaneous absorption
Remarks on result:
other: Dermal abs.: 0.00300 mg/cm2/event (LOW)

Applicant's summary and conclusion

Conclusions:
According to Danish (Q)SAR dermal absorption of 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate is low based on the estimated value 0.00300 mg/cm2/event.
Executive summary:

According to Danish (Q)SAR dermal absorption of 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate is low based on the estimated value 0.00300 mg/cm2/event.