Registration Dossier
Registration Dossier
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EC number: 226-501-6 | CAS number: 5413-60-5
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 5413-60-5
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- EPI Suite (DERMWIN) Various versions of EPI Suite dating back from 1990-2004.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- EPI Suite (DERMWIN)
- GLP compliance:
- no
Test material
- Reference substance name:
- 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- EC Number:
- 226-501-6
- EC Name:
- 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- Cas Number:
- 5413-60-5
- Molecular formula:
- C12H16O2
- IUPAC Name:
- 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- Details on test material:
- - Name of test material (as cited in study report): 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
- Substance type: Organic
- Physical state: Liquid
Constituent 1
- Radiolabelling:
- not specified
Test animals
- Species:
- other: no data
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
Results and discussion
Percutaneous absorption
- Remarks on result:
- other: Dermal abs.: 0.00300 mg/cm2/event (LOW)
Applicant's summary and conclusion
- Conclusions:
- According to Danish (Q)SAR dermal absorption of 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate is low based on the estimated value 0.00300 mg/cm2/event.
- Executive summary:
According to Danish (Q)SAR dermal absorption of 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate is low based on the estimated value 0.00300 mg/cm2/event.
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