Registration Dossier
Registration Dossier
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EC number: 222-392-4 | CAS number: 3458-28-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- column elution method
- Remarks:
- shake flask method
- Key result
- Water solubility:
- > 250 other: mg/mL
- Temp.:
- 20 °C
- Remarks on result:
- other: > 10% w/w
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
This study and the conclusions which are drawn from it fulfil the quality criteria (validity, reliability, repeatability).
The water solubility was > 250 mg/mL (> 250000 mg/L). - Executive summary:
Water solubility was determined in accordance with OECD guideline 105. The water solubility of D-Mannose was estimated from a preliminary trial that consisted of adding increasing amounts of reagent water (up to 4 mL) to a known mass of sample (~1.0g) until the sample was completely dissolved. The test substance solubility under the test condition was approximately 250 mg/mL. A definitive water solubility trial was not required according to the study protocol since the preliminary trial resulted in a water solubility value of greater than 10% w/w. The water solubility was > 250,000 mg/L (very soluble).
Reference
Description of key information
OECD Guideline 105
Key value for chemical safety assessment
- Water solubility:
- 250 000 mg/L
- at the temperature of:
- 20 °C
Additional information
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