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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
Qualifier:
no guideline available
Principles of method if other than guideline:
OECD Toolbox v3.1
Estimation for BOD by CATALOGIC: 301C v.08.12
Toolbox prediction report is attached in IUCLID
GLP compliance:
no
Specific details on test material used for the study:
Smiles: OCC{P-}(O)C{P-}(O)C{P+}(O)C{P+}(O)C=O
Key result
Parameter:
% degradation (O2 consumption)
Value:
81
St. dev.:
0.08
Remarks on result:
readily biodegradable based on QSAR/QSPR prediction
Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Conclusions:
81% degradation was predicted
Executive summary:

The catalogic model for biodegradation was used within the QSAR Toolbox. 81% degradation based on BOD was predicted indicating the test substance is readily biodegradable. Additional supporting documention is provided in the prediction report attached in IUCLID.

Description of key information

81% biodegradation based on BOD was predicted by QSAR using Catalogic 301C v.09.13 within the QSAR Toolbox indicating that the test substance is readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

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