Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
Reference
Endpoint:
skin sensitisation
Remarks:
other: Assessment based on an examination of the composition of the substance and the molecular structure of its components.
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was conducted based on an examination of the composition of the substance and the molecular structure of its components.
Qualifier:
no guideline required
Principles of method if other than guideline:
An assessment was conducted based on an examination of the composition of the substance and the molecular structure of its components.
GLP compliance:
no
Type of study:
other: Assessment based on an examination of the composition of the substance and the molecular structure of its components.

Based on an examination of the composition of the substance and the molecular structure of its components it is concluded that Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped is a skin sensitiser.

Interpretation of results:
Category 1 (skin sensitising) based on GHS criteria
Remarks:
Migrated information
Conclusions:
Based on an examination of the composition of the substance and the molecular structure of its components it is concluded that Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped is a potential skin sensitiser.
Executive summary:

The skin sensitisation potential of the substance was assessed based on an examination of the composition of the substance and the molecular structure of its components. The analysis of the substance identified the group of components with the function groups 'Olefins, monocyclic olefins and bicyclic olefins' as components with the potential to cause skin sensitisation. Amongst the components in this category, limonene (CAS 138-86-3), also referred to as dipentene, is known to be a Skin Sens. 1. Being present at 8.4%, we are far above the concentration of 1.0% that would trigger the classification of the UVCB as a Skin Sens. 1. The UVCB contains also 0.8% of iso-limonene, classified as skin sensitiser too. It is therefore concluded that Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped is a potential skin sensitiser.

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

The skin sensitisation potential of the substance was assessed based on an examination of the composition of the substance and the molecular structure of its components. The analysis of the substance identified the group of components with the function groups 'Olefins, monocyclic olefins and bicyclic olefins' as components with the potential to cause skin sensitisation. Amongst the components in this category, limonene (CAS 138-86-3), also referred to as dipentene, is known to be a Skin Sens. 1. Being present at 8.4%, we are far above the concentration of 1.0% that would trigger the classification of the UVCB as a Skin Sens. 1. The UVCB contains also 0.8% of iso-limonene, classified as skin sensitiser too. It is therefore concluded that  Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped

is a potential skin sensitiser.

Migrated from Short description of key information:
The substance is considered to be a potential skin sensitiser based on the concentration of limonene in the UVCB substance, which is known to be a Skin Sens. 1.

Justification for selection of skin sensitisation endpoint:
The skin sensitisation potential of the substance was assessed based on an examination of the composition of the substance and the molecular structure of its components.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

The substance is considered to be a potential skin sensitiser based on the concentration of limonene in the UVCB substance, which is known to be a Skin Sens. 1.