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Administrative data

Endpoint:
skin sensitisation
Remarks:
other: Assessment based on an examination of the composition of the substance and the molecular structure of its components.
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was conducted based on an examination of the composition of the substance and the molecular structure of its components.

Data source

Reference
Reference Type:
other: expert's assessment
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
An assessment was conducted based on an examination of the composition of the substance and the molecular structure of its components.
GLP compliance:
no
Type of study:
other: Assessment based on an examination of the composition of the substance and the molecular structure of its components.

Test material

Constituent 1
Reference substance name:
Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped
EC Number:
941-627-8
Molecular formula:
Not Applicable
IUPAC Name:
Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped
Constituent 2
Reference substance name:
Not assigned
IUPAC Name:
Not assigned
Test material form:
other: Liquid
Details on test material:
- Name of test material: Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped
- Physical state: Liquid
- Substance type: UVCB

Results and discussion

Any other information on results incl. tables

Based on an examination of the composition of the substance and the molecular structure of its components it is concluded that Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped is a skin sensitiser.

Applicant's summary and conclusion

Interpretation of results:
Category 1 (skin sensitising) based on GHS criteria
Remarks:
Migrated information
Conclusions:
Based on an examination of the composition of the substance and the molecular structure of its components it is concluded that Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped is a potential skin sensitiser.
Executive summary:

The skin sensitisation potential of the substance was assessed based on an examination of the composition of the substance and the molecular structure of its components. The analysis of the substance identified the group of components with the function groups 'Olefins, monocyclic olefins and bicyclic olefins' as components with the potential to cause skin sensitisation. Amongst the components in this category, limonene (CAS 138-86-3), also referred to as dipentene, is known to be a Skin Sens. 1. Being present at 8.4%, we are far above the concentration of 1.0% that would trigger the classification of the UVCB as a Skin Sens. 1. The UVCB contains also 0.8% of iso-limonene, classified as skin sensitiser too. It is therefore concluded that Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam-stripped is a potential skin sensitiser.

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