Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

Absorption, distribution, metabolism and excretion of 1,1,2,2 -tetrachloro-1,2 –difluoroethane are discussed under the ACGIH sheet for the substance.

The American Conference of Governmental Industrial Hygienists(ACGIH) is a professional association of industrial hygienists and practitioners of related professions. One of the goals of the association is to provide information and guideline on exposure limits of substances in order to advance worker protection, and to this purpose the available scientific data on substances are revised.

ACGIH summaries are based on a review of existing peer-reviewed scientific literature by committees of experts in public health and related sciences, therefore ACGIH is considered a reliable secondary source of information.


According to the reference, chlorofluorocarbons as 1,1,2,2 -tetrachloro-1,2 –difluoroethane, appear to be eliminated almost exclusively through the respiratory tract. Little, if any, chlorofluorocarbon or metabolite has ever been reported in urine and feces. 1,1,2,2 -tetrachloro-1,2 –difluoroethane is absorbed by the lung and undergoes little, if any, significant biotransformation.